Derek Shepherd

 Patrick Dempsey

Meredith Grey

Ellen Pompeo

Izzie Stevens

 Katherine Heigl

Cristina Yung

 Sandra Oh

Alex Karev

Justin Chambers

George O'Malley

 T.T. Knight

Miranda Bailey

 Chandra Wilson

 Addison Montgomery Shepherd

Kate Walsh

 Preston Burke

Isaiah Washington

  Richard Webber

James Pickens Jr.

 Callie Torres

Sara Ramirez

Finn  Dandrige

Chris O'Donnell

Mark Sloan

Eric Dane